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Group B Streptococcus Infection Market Outline: (Disease outline would assist in understanding disease progress, accordingly target appropriate segment for futuristic development)

The 9MM Group B Streptococcus Infection Drug Treatment Market is expected to offer an $ opportunity of USD XX Million over the analysis period. Market was estimated USD XX Million during 2023 and expected to grow at a significant CAGR XX% over the projected period. And by the end of 2033, the market is expected to touch USD XX Million.

Group B Streptococcus (GBS) bacteria most commonly live in people’s gastrointestinal and genital tracts. Typically, they do not cause any harm to human body, but sometime it invades in the body and causes various types of complications, which generally referred as infections. Their spectrum of infections is quite wide, may infect various body sites such as it may cause Bacteremia (bloodstream infection) and sepsis, Bone and joint infections, Pneumonia (lung infection), Skin and soft-tissue infections, Meningitis (infection of the tissue covering the brain and spinal cord) among others.

Long-term infections especially in babies and women could cause severe complications. Group B Streptococcus (GBS) is currently considered as prominent cause of infant morbidity and mortality

It is estimated that more than 10 million deaths will be caused by antimicrobial resistance (AMR) by 2050. Even now global health care bodies have raised serious concerns regarding antimicrobial resistance (AMR) across major markets. 

Patients on antibiotics for a longer period, are more susceptible to get bacterial infections. Lack of substantial progress in the developments of novel antibiotics limiting treatment options. Thus, majority of the patients rely on already available antibiotics leading to large number of AMR case around the world. According to World bank estimates, AMR could result in approximately USD 1 trillion an additional healthcare cost burden by 2050, and US$ 1 trillion to US$ 3.4 trillion GDP losses per year by 2030

Looking at above statistics, development of novel therapeutics option is imperative to provide curable treatment options. Studies meta-analysis demonstrated GBS infection causes a considerable burden of sepsis and meningitis in newborns.

Group B Streptococcus Infection Burden Analysis: (Result shown here is reflecting from meta-analysis, and CSP Analytics Solutions Analysis)

This section explored the epidemiology associated with Group B Streptococcus Infection

  • In the global context, higher prevalence registered in South East Asian countries
  • In the year, 2022 nearly 21.76 million pregnant women across the globe were colonised with GBS. Nearly 5 to 20% of non-pregnant women with GBS infection have urinary tract infections, and mostly such infections occur in elderly adults
  • Around 4.1% to 5.7% of babies who develop GBS disease are susceptible to die.
  • There are 10-15 cases in every 100,000 non-pregnant adults each year.​
  • There are around 25-30 cases in every 100,000 adults 65 years or older each year.​
  • Total infants’ infections cases in XX million (9MM)
  • Total pregnant women infections cases in XX million (9MM)
  • Total elderly infections cases in XX million (9MM)
  • XX million cases receiving treatment

Number of cases prevalent, annually diagnosed cases

Treatment Landscape: 

  • Treatment of Group B Streptococcus Infections requires holistic framework to address diverse set of patients accompanied with various therapeutic conditions (Co-morbidities). Collaboration among various specialties imperative to devise tailoring treatment plan. Efforts to promote antimicrobial stewardship and advocacy at patient and physician level is crucial approaches to mitigate the risk of antibiotic resistance.
  • Various treatment approaches involve while treating Group B Streptococcus Infection patients such as Antibiotic Therapy either as prophylactic and for treatment
  • Report evaluated players involves in the developments of vaccine technological platforms (Ex. Glycoconjugate vaccine) and their expected launches. Since there is no vaccine is licensed for the prevention of GBS.
  • Patients with different modalities, requires tailoring treatment options, since treatment accompanied with various challenges while treating pregnant women, neonatal and geriatric patients. 
  • Report explored, treatment strategies for different set of patients. What are the approaches embraced by physicians, while treating patients with co-morbidities and without co-morbidities
  • Group B Streptococcus Infection market is struggling to get an effective treatment. High spectrum antibiotics is currently the mainstay of therapy for patients
  • Recent clinical guidelines enable the streamlining the treatment approaches
  • Report, investigated patient segment targeted by each therapy type:
  • Report has examined the how many and what type of cases refer to which type of therapy based on experts’ opinion analysis.

Report also examined Approaches for Management

  1. Prophylaxis (Preventive Care)
  2. Treatment
DrugTargeted Patient Segment

Antibiotics

  • Prophylaxis (Prevention)
  • Treatment  
XX
VaccinesXX
                                                                                     Targeted Respondents Covered
Infectious Disease SpecialistsXX
General PhysicianXX
Orthopedic SurgeonsXX

Upcoming Therapy Assessment (Pipeline Analysis)

  • Report also provided promising therapy assessment including drugs, existing therapies, and upcoming therapy
  • Novel drug target assessment. For instance, development of vaccine-based therapy
  • Expected launch of key pipeline assets
  • Report also investigated novel therapy development (Ex. Vaccine), their potential health impact and cost-effectiveness, which has not been assessed globally.
  • Experts Opinion on the matter of accepting novel treatment options
  • Promising molecules advantages offer over existing therapy
  • Impact assessment of pipeline assets
  • Drug analogue analysis
  • Expected annual cost of therapy

Recent Advancements:

Pfizer’s Group B Streptococcus Vaccine Candidate received FDA Breakthrough Therapy Designation to Prevent Infection in Infants Via Immunization of Pregnant Women

Trial activities supported by funding organization, such as in this case grant received from the Bill & Melinda Gates Foundation, which endorsed the ongoing Phase 2 clinical trial of GBS6.

Market Segmentation Analysis by:

  • By Cases Type
    • Early-Onset Disease
    • Late-Onset Disease
  • By Infection Type
    • Maternal Colonization
    • Neonatal Infection
    • Adult Infections
  • By Treatment Type
    • Antibiotics
      • Prophylaxis (Prevention) Treatment
  • By Gender
    • Female
    • Male
  • By Route of Administration
    • Oral
    • Injectable
  • By Infections Source
    • Hospital-acquired Infections
    • Community-acquired Infections

Market Dynamics: Explored in the report

  • Untreated Prevalent Pool of Group B Streptococcus Infection
  • Huge medical unmet need
  • Rising Incidence and prevalence of GBS Infections
  • Proliferation of novel treatment options
  • Increasing awareness and screening programs

Continued investments in research and developmental activities by pharmaceutical companies, biotechnology firms, and academic institutions contribute to the development of innovative diagnostic tools, treatments, and vaccines for GBS infection, further driving market growth.

Market Challenges: Explored in the report

  • Inadequate efficacious treatment options
  • Surging antibiotic resistance cases
  • Long-term treatment consequences
  • Neonatal Sepsis Management: Neonatal GBS sepsis requires prompt recognition and treatment with appropriate antibiotics to prevent serious complications such as meningitis and long-term neurodevelopmental sequelae. However, distinguishing GBS sepsis from other neonatal infections can be challenging, and delays in diagnosis and treatment can significantly impact outcomes.
  • Treating AMR cases
  • Research gap
  • Cost of therapy
  • Treatment compliance and adherence

 

Mapped Geography: Nine Major Markets (9MM) 

Report has fragmented the total market into five regions such as:

  • United States
  • 5-Europe
  • Germany
  • France
  • Italy
  • Spain
  • United Kingdom
  • Rest of Europe
  • China
  • Japan
  • India
  • RoW (Rest of World)

Each mapped region has been examined at granular level based on below parameters:

  • United States Group B Streptococcus Infection Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Healthcare Provider Preferences (primary care physicians, infectious disease specialists, urologists, etc.)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Market Unmet Need Analysis
  • 5-Europe Group B Streptococcus Infection Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
    • By Country
      • United Kingdom
      • Germany
      • France
      • Italy
      • Spain
      • Rest of Europe
  • China Group B Streptococcus Infection Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
  • India Group B Streptococcus Infection Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
  • Japan Group B Streptococcus Infection Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
  • Rest of the World Group B Streptococcus Infection Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)

Competitive Landscape (Existing and Pipeline Players): 

Players in Market Space - Players explored in the report has been analyzed at various parameters. Analysis done around, product offerings, pipeline assets, In-licensing and out-licensing opportunities, financial health, market share, collaboration and partnership, patents, funding secures, technology outlook, future strategic move and investment.

Companies Profile:

  • Pfizer Inc.
  • GlaxoSmithKline (GSK)
  • Sanofi Pasteur
  • Merck & Co., Inc.
  • NovaDigm Therapeutics
  • Evolve Biosystems
  • Others