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Metastatic castration-resistant prostate cancer (mCRPC) Market Outline: 

The 9MMMetastatic castration-resistant prostate cancer (mCRPC) Drug Treatment Market is expected to offer an $ opportunity of USD XX Million over the analysis period. Market was estimated USD XX Million during 2023 and expected to grow at a significant CAGR XX% over the projected period. And by the end of 2033, the market is expected to touch USD XX Million.

This form of cancer refers, when prostate cancer advanced to an stage and spreads beyond the prostate gland to other parts of the body. With Metastatic Castration-Resistant Prostate Cancer (mCRPC), hormone therapy no longer stops cancer growth. Common symptoms are Trouble urinating, blood in urine, Weight loss, Shortness of breath, Bone pain among others.

Report has covered granular-level analysis in each mapped market

Metastatic castration-resistant prostate cancer (mCRPC), Disease Burden Analysis: (Result shown here is refelecting from studies metanalysis, and CSP Analytics Solutions Analysis)

  •  The prevalence of mCRPC estimated approximately 1.2% to 2.1% of prostate cancer cases
  • Around 25% of patients with mCRPC have gene alterations in the tumor associated with homologous recombination repair
  • Annually there are approximately 1,140,042 new cases of prostate cancer (PC) diagnosed across the globe
  • Prostate Cancer Prevalent Pool XXXX (Absolute value)
    • Non metastatic (Absolute value)
      • T0/TX (Absolute value)
      • T1/T2 (Absolute value)
      • T3/T4 (Absolute value)
    • Metastatic (Absolute value)
      • mHSPC (Absolute value)
      • mCRPC (Absolute value)

Treatment Landscape: 

  • Metastatic castration-resistant prostate cancer (mCRPC) market is struggling to get an effective treatment
  • Advancement in biomarkers is essential for developing a targeted therapy
  • Chemotherapy is currently the mainstay of systemic therapy for patients
  • The developement of Bone-targeted Agents, PARP Inhibitors, Radiopharmaceuticals,  expected to change the therapeutic landscape of Metastatic castration-resistant prostate cancer (mCRPC)
  • Recent clinical guidelines enable the streamlining the treatment approaches
  • Report, investigated patient segment targeted by each therapy type:
  • Report has examined the how many and what type of cases refer to which type of therapy based on experts opinion analysis.
  • Report also examined Approaches for Management
    • First-line of therapy
    • Second-line of therapy
DrugTargeted Patient Segment
Androgen Deprivation Therapy (ADT)XX
Second-generation Androgen Receptor Signaling InhibitorsXX
ChemotherapyXX
RadiopharmaceuticalsXX
ImmunotherapyXX
PARP InhibitorsXX
Bone-targeted AgentsXX

Upcoming Therapy Assessment (Pipeline Analysis)

  • Report also provided promising therapy assessment including drugs, existing therapies and upcoming therapy
  • Novel drug target assessmment. For instance. Sipuleucel-T (S-T), a therapeutic cancer vaccine, is an autologous cellular immunotherapy that has been found to lower the risk of mortality in mCRPC patients
  • Expected launch of key pipeline assets
  • Promising molecules advantages offer over existing therapy
  • Impact assessment of pipeline assets
  • Drug analogue analysis
  • Expected annual cost of therapy

Market Segmentation Analysis by:

  • By Type of Therapy:
    • Second-generation Androgen Receptor Signaling Inhibitors
    • Chemotherapy
    • Immunotherapy
    • Radiopharmaceuticals
    • PARP Inhibitors
    • Targeted Therapies
    • Bone-targeted Agents
    • Experimental Therapies
      • CAR-T cell Therapy
      • Bispecific Antibodies
      • Novel Hormonal Agents
  • By Line of Therapy:
    • First-line of therapy
    • Second-line of therapy
  • By Therapy Modality:
    • Monotherapy
    • Combination Therapy

Market Dynamics: Explored in the report

  • Untreated Prevalent Pool of Metastatic castration-resistant prostate cancer (mCRPC)
  • Significant development in biomarkers
  • Conducive reimbursement, pricing strategies, and market access ecosystems
  • Huge medical unmet need

Market Challenges: Explored in the report

  • Inadequate efficacious treatment options
  • Lack of timely diagnosis
  • Research gap
  • Cost of therapy
  • Treatment compliance and adherence

Recent Developments:

  • March, 2022: FDA approved Pluvicto (lutetium Lu 177 vipivotide tetraxetan, Advanced Accelerator Applications USA, Inc., a Novartis company) for the treatment of adult patients with prostate-specific membrane antigen (PSMA)-positive metastatic castration-resistant prostate cancer (mCRPC) who have been treated with androgen receptor (AR) pathway inhibition and taxane-based chemotherapy.

Mapped Geography: Nine Major Markets (9MM) 

Report has fragmented the total market into five regions such as:

  • United States
  • 5-Europe
    • Germany
    • France
    • Italy
    • Spain
    • United Kingdom
    • Rest of Europe
  • China
  • Japan
  • India
  • RoW (Rest of World)

 

Each mapped region has been examined at granular level based on below parameters:

  • United States Metastatic castration-resistant prostate cancer (mCRPC) Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
  • 5-Europe Metastatic castration-resistant prostate cancer (mCRPC) Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
    • By Country
      • United Kingdom
      • Germany
      • France
      • Italy
      • Spain
      • Rest of Europe
  • China Metastatic castration-resistant prostate cancer (mCRPC) Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
  • India Metastatic castration-resistant prostate cancer (mCRPC) Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
  • Japan Metastatic castration-resistant prostate cancer (mCRPC) Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)
  • Rest of the World Metastatic castration-resistant prostate cancer (mCRPC) Drug Treatment Market
    • Market Size and Forecast Model 2023-2033
    • Disease Overview
    • Current Treatment Approaches
    • Key Opinion Leader (KOL) Views
    • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
    • Diagnosis and Treatment Guidelines
    • Drug Share Analysis (%)
    • Drug Treatment Adherence and Compliance Rate (%)
    • Annual Cost of Therapy
    • Current Treatment Landscape and Upcoming therapy Assessment
    • Market Unmet Need Analysis
    • Key Players in the Market and their Market share (%)

Competitive Landscape (Existing and Pipeline Players): 

Players in Market Space - Players explored in the report has been analyzed at various parameters. Analysis done around, product offerings, pipeline assets, In-licensing and out-licensing opportunities, financial health, market share, collaboration and partnership, patents, funding secures, technology outlook, future strategic move and investment.

Companies Profile:

  • Janssen Biotech (a subsidiary of Johnson & Johnson)
  • Astellas Pharma
  • Bristol Myers Squibb (BMS)
  • Pfizer
  • AstraZeneca
  • Sanofi Genzyme
  • Clovis Oncology
  • Exelixis
  • Merck & Co. (MSD outside the United States and Canada)
  • Bayer
  • Novartis
  • Seattle Genetics
  • Others

Reason to buy this report: 

  • Fostering Understanding on Metastatic castration-resistant prostate cancer (mCRPC) Drug Treatment Market
  • In Order to Understand the Market Potential
  • Opportunity Analysis (exist in the market for players)
  • Clinical Developments in the market
  • To Know Current and Future Market Trends
  • Key Players and their Key Strategic Move