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Non-Erosive Reflux Disease (NERD) Market Outline: 

The 9MM Non-Erosive Reflux Disease (NERD) Treatment Market is expected to offer an $ opportunity of USD XX Million over the analysis period. Market was estimated USD XX Million during 2023 and expected to grow at a significant CAGR XX% over the projected period. And by the end of 2033, the market is expected to touch USD XX Million.

Pipeline drugs expected to provide an opportunity of more than USD 7.5 billion during the forecast year.

+30 ongoing clinical trials

Disease Overview

Non-erosive reflux disease (NERD) is a subtype of gastroesophageal reflux disease (GERD) characterized by typical GERD symptoms, such as heartburn and acid regurgitation, in the absence of esophageal mucosal injury.

Report has deeply investigated patient’s presentation and tailored treatment

Report has Covered Granular-level Analysis in Each Mapped Market

Non-Erosive Reflux Disease (NERD) Disease Burden Analysis: (Result shown here is reflecting from meta-analysis, and CSP Analytics Solutions Analysis)

  • Our analysis shows that, the prevalence of Non-Erosive Reflux Disease (NERD) varies across regions but, its overall prevalence ranges from 50% and 70% of the GERD population especially in western countries. Moreover, annual progression rates for NERD to ERD ranged from 0% to 30%
  • This section explored the epidemiology associated with Non-Erosive Reflux Disease (NERD) across regions.
  • Experts indicated prevalence increased significantly across regions, but gaps in estimates persist. 
  • Our research report has provided crystal clear view of prevalent pool across regions. Since epidemiology estimation accompanied with lot of complexity, our report has streamlined the estimation process for enhancing market understanding.
  • Report has also highlighted, impact of improvements in diagnosis, on diagnosis rate (%).  

Non-Erosive Reflux Disease (NERD) Cases: 9MM 

  • Non-Erosive Reflux Disease (NERD) accounts for XX million cases of Gastroesophageal reflux disease (GERD) in 9MM
  • Non-Erosive Reflux Disease (NERD) accounts for XX million cases of Gastroesophageal reflux disease (GERD) in United States
  • Non-Erosive Reflux Disease (NERD) accounts for XX million cases of Gastroesophageal reflux disease (GERD) in China
  • Non-Erosive Reflux Disease (NERD) accounts for XX million cases of Gastroesophageal reflux disease (GERD) in India
  • Non-Erosive Reflux Disease (NERD) accounts for XX million cases of Gastroesophageal reflux disease (GERD) in Japan
  • Non-Erosive Reflux Disease (NERD) accounts for XX million cases of Gastroesophageal reflux disease (GERD) in Rest of World

Treatment Landscape: 

This report section deals with the treatment strategies adopted by healthcare professional while dealing across patients’ segments.  Also provided gaps in current treatment and upcoming treatment options. 

  • Currently, no vaccines are available for the prevention of RSV infections
  • Treatment of Non-Erosive Reflux Disease (NERD)’s requires holistic framework to address diverse set of patients accompanied with various type of Non-Erosive Reflux Disease (NERD). Collaboration among various specialties imperative to devise tailoring treatment plan. Efforts to encourage diagnosis rate and advocacy at patient and physician level is crucial to provide better therapeutic options.
  • Report section covers detailed around various types of available treatments
    • OTC Drugs
    • Prescription
    • Combination Therapy
    • Complementary Therapies
  • Also covers patient segment targeted by each therapy type: This section address concerns regarding unaddressed patient pool 
  • Several companies and institutions collaborating to bring out the appropriate treatment solutions
  • Our report analysis revealed that, there are tremendous opportunities exits in the market in order to close the current market gaps
  • Recent clinical guidelines enable the streamlining the treatment approaches
  • Report has examined the how many and what type of cases refer to which type of therapy based on experts’ opinion analysis.

Patient Segment Coverage:

DrugTargeted Patient Segment
OTC DrugsXX
PrescriptionXX
Combination TherapyXX
Complementary TherapiesXX

Upcoming Therapy Assessment (Pipeline Analysis)

  • Report also provided promising therapy assessment including existing therapies, and upcoming therapy
  • Novel drug target assessment
  • Comparable efficacy and safety profiles of key drugs prescribed in each mapped geography
  • Expected launch of key pipeline assets
  • Report also investigated novel therapy development
  • Experts Opinion on the matter of accepting novel treatment options
  • Promising molecules advantages offer over existing therapy
  • Impact assessment of pipeline assets
  • Drug analogue analysis
  • Expected annual cost of therapy
  • Market space expected to be captured by emerging therapeutic options

Market Segmentation Analysis by:

  • By Treatment Type
    • OTC
      • Antacids
      • H2-receptor antagonists (H2RAs)
      • Proton pump inhibitors (PPIs)
    • Prescription
      • Prokinetics
      • Alginate-based formulations
      • Proton pump inhibitors (PPIs)
    • Combination Therapy
  • By Severity
    • Mild
    • Moderate
    • Severe
  • By Route of Administration
    • Injectable treatments
    • Oral treatments
    • Infusion treatments
  • By Gender
    • Male
    • Female

Market Enablers: Explored in the report

  • Increasing Prevalence: The prevalence of GERD, including NERD, has been on the rise globally due to factors such as changes in lifestyle, dietary habits, and obesity rates. This increasing prevalence drives demand for diagnostic and treatment options specifically tailored to NERD.
  • Untreated Prevalent Pool of Non-Erosive Reflux Disease (NERD)
  • Huge medical unmet need
  • Demand for Effective Treatment Options
  • Proliferation of novel treatment options
  • Advent of emerging therapy for developing tailoring treatment
  • Continued investments in research and developmental activities by pharmaceutical companies, and academic institutions contribute to the development of innovative diagnostic tools, treatments, and other therapies.

Market Challenges: Explored in the report

  • Patient Heterogeneity: Patients with NERD exhibit diverse symptoms and responses to treatment. Some may experience severe symptoms despite minimal esophageal inflammation, while others may have mild symptoms despite significant mucosal damage. This heterogeneity complicates treatment strategies and clinical trials.
  • Limited Treatment Efficacy
  • Chronic Nature and Recurrence
  • Research and development gaps
  • Lack of adequate treatment compliance and adherence

Mapped Geography: Nine Major Markets (9MM) 

Report has fragmented the total market into five regions such as:

  • United States
  • 5-Europe
    • Germany
    • France
    • Italy
    • Spain
    • United Kingdom
    • Rest of Europe
  • China
  • Japan
  • India
  • RoW (Rest of World)

Each mapped region has been examined at granular level based on below parameters:

United States Non-Erosive Reflux Disease (NERD) Treatment Market

  • Market Size and Forecast Model 2023-2033
  • Disease Overview
  • Current Treatment Approaches
  • Key Opinion Leader (KOL) Views
  • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
  • Diagnosis and Treatment Guidelines
  • Drug Share Analysis (%)
  • Drug Treatment Adherence and Compliance Rate (%)
  • Annual Cost of Therapy
  • Market Unmet Need Analysis

5-Europe Non-Erosive Reflux Disease (NERD) Treatment Market

  • Market Size and Forecast Model 2023-2033
  • Disease Overview
  • Current Treatment Approaches
  • Key Opinion Leader (KOL) Views
  • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
  • Diagnosis and Treatment Guidelines
  • Drug Share Analysis (%)
  • Drug Treatment Adherence and Compliance Rate (%)
  • Annual Cost of Therapy
  • Current Treatment Landscape and Upcoming therapy Assessment
  • Market Unmet Need Analysis
  • Key Players in the Market and their Market share (%)

By Country

  • United Kingdom
  • Germany
  • France
  • Italy
  • Spain
  • Rest of Europe

China Non-Erosive Reflux Disease (NERD) Treatment Market

  • Market Size and Forecast Model 2023-2033
  • Disease Overview
  • Current Treatment Approaches
  • Key Opinion Leader (KOL) Views
  • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
  • Diagnosis and Treatment Guidelines
  • Drug Share Analysis (%)
  • Drug Treatment Adherence and Compliance Rate (%)
  • Annual Cost of Therapy
  • Current Treatment Landscape and Upcoming therapy Assessment
  • Market Unmet Need Analysis
  • Key Players in the Market and their Market share (%)

India Non-Erosive Reflux Disease (NERD) Treatment Market

  • Market Size and Forecast Model 2023-2033
  • Disease Overview
  • Current Treatment Approaches
  • Key Opinion Leader (KOL) Views
  • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
  • Diagnosis and Treatment Guidelines
  • Drug Share Analysis (%)
  • Drug Treatment Adherence and Compliance Rate (%)
  • Annual Cost of Therapy
  • Current Treatment Landscape and Upcoming therapy Assessment
  • Market Unmet Need Analysis
  • Key Players in the Market and their Market share (%)

Japan Non-Erosive Reflux Disease (NERD) Treatment Market

  • Market Size and Forecast Model 2023-2033
  • Disease Overview
  • Current Treatment Approaches
  • Key Opinion Leader (KOL) Views
  • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
  • Diagnosis and Treatment Guidelines
  • Drug Share Analysis (%)
  • Drug Treatment Adherence and Compliance Rate (%)
  • Annual Cost of Therapy
  • Current Treatment Landscape and Upcoming therapy Assessment
  • Market Unmet Need Analysis
  • Key Players in the Market and their Market share (%)

Rest of the World Non-Erosive Reflux Disease (NERD) Treatment Market

  • Market Size and Forecast Model 2023-2033
  • Disease Overview
  • Current Treatment Approaches
  • Key Opinion Leader (KOL) Views
  • Disease Burden Analysis (Prevalence, Diagnosed, Treatable Prevalent Pool Analysis)
  • Diagnosis and Treatment Guidelines
  • Drug Share Analysis (%)
  • Drug Treatment Adherence and Compliance Rate (%)
  • Annual Cost of Therapy
  • Current Treatment Landscape and Upcoming therapy Assessment
  • Market Unmet Need Analysis
  • Key Players in the Market and their Market share (%)

Competitive Landscape (Existing and Pipeline Players): 

Players in Market Space - Players explored in the report has been analyzed at various parameters. Analysis done around, product offerings, pipeline assets, In-licensing and out-licensing opportunities, financial health, market share, collaboration and partnership, patents, funding secures, technology outlook, future strategic move and investment.

Companies Profile:

  • AstraZeneca
  • Takeda Pharmaceutical Company
  • Pfizer
  • Ironwood Pharmaceuticals
  • Johnson & Johnson
  • Sun Pharmaceuticals
  • Cipla
  • Il-Yang Pharm. Co., Ltd.
  • Yooyoung Pharmaceutical Co., Ltd.
  • Others

Pipeline Companies:

  • Daewoong Pharmaceutical Co. LTD.
  • Chong Kun Dang Pharmaceutical
  • Il-Yang Pharm. Co., Ltd.
  • Phathom Pharmaceuticals, Inc.
  • Eisai Co., Ltd.

Reason to buy this report:

  • Fostering Understanding on Non-Erosive Reflux Disease (NERD) Disease Treatment Market
  • In Order to Understand the Market Potential 
  • Opportunity Analysis (exist in the market for players)
  • Clinical Developments in the market
  • To Know Current and Future Market Trends
  • Key Players and their Key Strategic Move